The Swiss Federal Office of Public Health recommends regularly descaling water heating systems and provides information on the influence of limescale deposits on Legionella bacteria. Here is a summary of the most interesting findings from the 115-page recommendation report:
Interested in the full report? Click here. 
Mediagon limescale protection combats Legionella indirectly by depriving them of their breeding ground and breeding ground – namely limescale and rust – in the pipe system.